PAIP2 antibody (N-Term)

Catalog No. ABIN1539498

Product Details anti-PAIP2 Antibody

Target: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Binding Specificity: AA 7-34, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAIP2 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, C

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PAIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-34 amino acids from the N-terminal region of human PAIP2.

Clone: RB30366

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PAIP2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for PAIP2

Target: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Alternative Name: PAIP2 (PAIP2 Products)

Synonyms: PAIP2A antibody, DKFZp469O1314 antibody, 2310050K10Rik antibody, AU045972 antibody, paip2 antibody, poly(A) binding protein interacting protein 2 antibody, polyadenylate-binding protein-interacting protein 2 antibody, poly(A) binding protein interacting protein 2B L homeolog antibody, PAIP2 antibody, Paip2 antibody, paip2b.L antibody

Background: PAIP2 acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.

Molecular Weight: 14984

Gene ID: 51247

NCBI Accession: NP_001028284, NP_057564

UniProt: Q9BPZ3