This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This FBXL8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-83 amino acids from the N-terminal region of human FBXL8.
FBXL8 antibody, zgc:123259 antibody, FBL8 antibody, RGD1566420 antibody, F-box and leucine rich repeat protein 8 antibody, F-box and leucine-rich repeat protein 8 antibody, F-box and leucine-rich repeat protein 8 L homeolog antibody, FBXL8 antibody, fbxl8 antibody, fbxl8.L antibody, Fbxl8 antibody
Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78 % sequence identity with the mouse protein.