TPP1 antibody (N-Term)

Catalog No. ABIN1539423

Product Details anti-TPP1 Antibody

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Binding Specificity: AA 6-34, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPP1 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human TPP1.

Clone: RB36843

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: TPP1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for TPP1

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Alternative Name: TPP1 (TPP1 Products)

Synonyms: cln2 antibody, fa01b09 antibody, im:7149243 antibody, wu:fa01b09 antibody, CLN2 antibody, LPIC antibody, TPP-1 antibody, TPP-I antibody, Cln2 antibody, tripeptidyl peptidase I antibody, tripeptidyl-peptidase 1 antibody, tripeptidyl peptidase 1 antibody, tpp1 antibody, NAEGRDRAFT_78259 antibody, MCYG_00184 antibody, MGYG_05881 antibody, MGYG_00757 antibody, TPP1 antibody, Tpp1 antibody

Background: This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

Molecular Weight: 61248

Gene ID: 1200

NCBI Accession: NP_000382

UniProt: O14773

Pathways: Cell Division Cycle, ER-Nucleus Signaling