PACRG antibody (N-Term)

Catalog No. ABIN1539399

Product Details anti-PACRG Antibody

Target: PACRG (PARK2 Co-Regulated (PACRG))

Binding Specificity: AA 46-74, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PACRG antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PACRG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-74 amino acids from the N-terminal region of human PACRG.

Clone: RB36712

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PACRG Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for PACRG

Target: PACRG (PARK2 Co-Regulated (PACRG))

Alternative Name: PACRG (PACRG Products)

Synonyms: PACRG antibody, GLUP antibody, HAK005771 antibody, PARK2CRG antibody, RP3-495O10.2 antibody, zgc:101786 antibody, RGD1561027 antibody, 1700008H23Rik antibody, parkin coregulated antibody, PARK2 co-regulated antibody, PARK2 coregulated antibody, PACRG antibody, pacrg antibody, Pacrg antibody

Background: This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 33342

Gene ID: 135138

NCBI Accession: NP_001073847, NP_001073848, NP_689623

UniProt: Q96M98