RCAN1 antibody (N-Term)

Catalog No. ABIN1539360

Product Details anti-RCAN1 Antibody

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Binding Specificity: AA 41-68, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RCAN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RCAN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-68 amino acids from the N-terminal region of human RCAN1.

Clone: RB36242

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: RCAN1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for RCAN1

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Alternative Name: RCAN1 (RCAN1 Products)

Synonyms: ADAPT78 antibody, CSP1 antibody, DSC1 antibody, DSCR1 antibody, MCIP1 antibody, RCN1 antibody, RCAN1 antibody, 2410048A02Rik antibody, AA408855 antibody, AI429645 antibody, AL024459 antibody, AV028423 antibody, Adapt78 antibody, CALP1L antibody, Dscr1 antibody, Mcip1 antibody, dscr1 antibody, rcan1 antibody, wu:fr92c05 antibody, adapt78 antibody, csp1 antibody, dsc1 antibody, mcip1 antibody, MGC53636 antibody, rcn1 antibody, MGC69428 antibody, regulator of calcineurin 1 antibody, regulator of calcineurin 1b antibody, regulator of calcineurin 1 L homeolog antibody, Down syndrome critical region gene 1 antibody, RCAN1 antibody, Rcan1 antibody, rcan1b antibody, rcan1.L antibody, dscr1 antibody, rcan1 antibody

Background: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.

Molecular Weight: 28079

Gene ID: 1827

NCBI Accession: NP_004405, NP_981962, NP_981963

UniProt: P53805

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development