RCAN1 antibody (N-Term)
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- Target See all RCAN1 Antibodies
- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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Binding Specificity
- AA 41-68, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RCAN1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Predicted Reactivity
- M
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This RCAN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-68 amino acids from the N-terminal region of human RCAN1.
- Clone
- RB36242
- Isotype
- Ig Fraction
- Top Product
- Discover our top product RCAN1 Primary Antibody
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- Application Notes
- IF: 1:10~50. WB: 1:1000. WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- RCAN1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- Expiry Date
- 6 months
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- Target
- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
- Alternative Name
- RCAN1 (RCAN1 Products)
- Background
- The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.
- Molecular Weight
- 28079
- Gene ID
- 1827
- NCBI Accession
- NP_004405, NP_981962, NP_981963
- UniProt
- P53805
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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