IL28B antibody (N-Term)

Catalog No. ABIN1539309

Product Details anti-IL28B Antibody

Target: IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))

Binding Specificity: AA 34-63, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL28B antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IL28B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-63 amino acids from the N-terminal region of human IL28B.

Clone: RB36625

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: IL28B Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

References for anti-IL28B antibody (ABIN1539309)

Ferraris, Chandra, Panigrahi, Aboulnasr, Chava, Kurt, Pawlotsky, Wilkens, Osterlund, Hartmann, Balart, Wu, Dash: "Cellular Mechanism for Impaired Hepatitis C Virus Clearance by Interferon Associated with IFNL3 Gene Polymorphisms Relates to Intrahepatic Interferon-λ Expression." in: The American journal of pathology, Vol. 186, Issue 4, pp. 938-51, (2016) (PubMed).

Target Details for IL28B

Target: IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))

Alternative Name: IL28B (IL28B Products)

Synonyms: Il28b antibody, IFL-1 antibody, IL-28B antibody, INF-alpha antibody, INF-lambda antibody, Il28 antibody, IL28B antibody, IL28C antibody, interferon, lambda 3 antibody, interferon lambda 3 antibody, Ifnl3 antibody, IFNL3 antibody

Background: This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).

Molecular Weight: 21706

Gene ID: 282617

NCBI Accession: NP_742151

UniProt: Q8IZI9