ESX Homeobox 1 antibody (N-Term)

Catalog No. ABIN1539252

Product Details anti-ESX Homeobox 1 Antibody

Target: ESX Homeobox 1 (ESX1)

Binding Specificity: AA 28-55, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESX Homeobox 1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ESX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-55 amino acids from the N-terminal region of human ESX1.

Clone: RB37249

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000-1:2000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: ESX1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for ESX Homeobox 1

Target: ESX Homeobox 1 (ESX1)

Alternative Name: ESX1 (ESX1 Products)

Synonyms: ESX1L antibody, ESXR1 antibody, Spx1 antibody, ESX homeobox 1 antibody, extraembryonic, spermatogenesis, homeobox 1 antibody, ESX1 antibody, Esx1 antibody

Background: This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus. In contrast to human, the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue. This gene likely plays a role in placental development and spermatogenesis.

Molecular Weight: 44297

Gene ID: 80712

NCBI Accession: NP_703149

UniProt: Q8N693