PCDHGC4 antibody (N-Term)

Catalog No. ABIN1539248

Product Details anti-PCDHGC4 Antibody

Target: PCDHGC4 (Protocadherin gamma Subfamily C, 4 (PCDHGC4))

Binding Specificity: AA 265-291, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHGC4 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCDHGC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-291 amino acids from the N-terminal region of human PCDHGC4.

Clone: RB39610

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PCDHGC4 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for PCDHGC4

Target: PCDHGC4 (Protocadherin gamma Subfamily C, 4 (PCDHGC4))

Alternative Name: PCDHGC4 (PCDHGC4 Products)

Synonyms: PCDH-GAMMA-C4 antibody, protocadherin gamma c4 antibody, protocadherin gamma subfamily C, 4 antibody, Pcdhgc4 antibody, PCDHGC4 antibody

Background: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Molecular Weight: 101214

Gene ID: 56098

NCBI Accession: NP_061751, NP_115782

UniProt: Q9Y5F7