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ULBP2 antibody (AA 88-116)

ULBP2 Reactivity: Human WB Host: Rabbit Polyclonal RB37009 unconjugated
Catalog No. ABIN1538674
  • Target See all ULBP2 Antibodies
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    Binding Specificity
    • 6
    • 6
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 88-116
    Reactivity
    Human
    Host
    • 16
    • 5
    Rabbit
    Clonality
    • 18
    • 3
    Polyclonal
    Conjugate
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    This ULBP2 antibody is un-conjugated
    Application
    • 19
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ULBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the Central region of human ULBP2.
    Clone
    RB37009
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ULBP2 Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    ULBP2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Expiry Date
    6 months
  • Target
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    Alternative Name
    ULBP2 (ULBP2 Products)
    Synonyms
    N2DL2 antibody, RAET1H antibody, UL16 binding protein 2 antibody, NKG2D ligand 2-like antibody, ULBP2 antibody, LOC100355436 antibody
    Background
    Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.
    Molecular Weight
    27368
    Gene ID
    80328
    NCBI Accession
    NP_079493
    UniProt
    Q9BZM5
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