This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This MOG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-109 amino acids from the Central region of human MOG.
The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.