MKL1 antibody (AA 497-525)

Catalog No. ABIN1538460

Product Details anti-MKL1 Antibody

Target: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Binding Specificity: AA 497-525

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKL1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MKL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 497-525 amino acids from the Central region of human MKL1.

Clone: RB39491

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: MKL1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for MKL1

Target: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Alternative Name: MKL1 (MKL1 Products)

Synonyms: MKL1 antibody, BSAC antibody, MAL antibody, MRTF-A antibody, Mrtf-a antibody, mrtf-a antibody, mrtfa antibody, AI852829 antibody, AMKL antibody, AW743281 antibody, AW821984 antibody, Bsac antibody, Mal antibody, Mrtf-A antibody, megakaryoblastic leukemia (translocation) 1 antibody, megakaryoblastic leukemia 1 protein antibody, megakaryoblastic leukemia (translocation) 1 S homeolog antibody, MKL (megakaryoblastic leukemia)/myocardin-like 1 antibody, MKL1 antibody, mkl1 antibody, Mkl1 antibody, mkl1.S antibody

Background: The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia.

Molecular Weight: 98919

Gene ID: 57591

NCBI Accession: NP_065882

UniProt: Q969V6