Cyclin F antibody (AA 496-524)

Catalog No. ABIN1538458

Product Details anti-Cyclin F Antibody

Target: Cyclin F (CCNF)

Binding Specificity: AA 496-524

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin F antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CCNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 496-524 amino acids from the Central region of human CCNF.

Clone: RB24427

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CCNF Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for Cyclin F

Target: Cyclin F (CCNF)

Alternative Name: CCNF (CCNF Products)

Synonyms: Cyclin-F antibody, DKFZp459P0432 antibody, FBX1 antibody, FBXO1 antibody, CycF antibody, Fbxo1 antibody, cb443 antibody, zgc:77240 antibody, cyclin F antibody, cyclin F L homeolog antibody, CCNF antibody, ccnf.L antibody, ccnf antibody, Ccnf antibody

Background: This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified.

Molecular Weight: 87640

Gene ID: 899

NCBI Accession: NP_001752

UniProt: P41002