SH3BP1 antibody (AA 419-446)

Catalog No. ABIN1538408

Product Details anti-SH3BP1 Antibody

Target: SH3BP1 (SH3-Domain Binding Protein 1 (SH3BP1))

Binding Specificity: AA 419-446

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3BP1 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SH3BP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 419-446 amino acids from the Central region of human SH3BP1.

Clone: RB36508

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: SH3BP1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for SH3BP1

Target: SH3BP1 (SH3-Domain Binding Protein 1 (SH3BP1))

Alternative Name: SH3BP1 (SH3BP1 Products)

Synonyms: ARHGAP43 antibody, 3BP-1 antibody, SH3BP1 antibody, SH3 domain binding protein 1 antibody, SH3-domain binding protein 1 antibody, SH3 domain-binding protein 1 antibody, SH3BP1 antibody, Sh3bp1 antibody, LOC100398528 antibody

Background: SH3BP1 binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho-or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity).

Molecular Weight: 75713

Gene ID: 23616

NCBI Accession: NP_061830

UniProt: Q9Y3L3