This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This IQCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-411 amino acids from the Central region of human IQCB1.
This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants.