PPP1R16B antibody (AA 372-399)

Catalog No. ABIN1538368

Product Details anti-PPP1R16B Antibody

Target: PPP1R16B (Protein Phosphatase 1, Regulatory Subunit 16B (PPP1R16B))

Binding Specificity: AA 372-399

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R16B antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PPP1R16B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 372-399 amino acids from the Central region of human PPP1R16B.

Clone: RB37604

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PPP1R16B Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

References for anti-PPP1R16B antibody (ABIN1538368)

Boratkó, Péter, Csortos: "Regulation of merlin by protein phosphatase 1-TIMAP and EBP50 in endothelial cells." in: The international journal of biochemistry & cell biology, Vol. 82, pp. 10-17, (2017) (PubMed).

Boratkó, Csortos: "PKC mediated phosphorylation of TIMAP regulates PP1c activity and endothelial barrier function." in: Biochimica et biophysica acta. Molecular cell research, Vol. 1864, Issue 2, pp. 431-439, (2017) (PubMed).

Boratkó, Veréb, Petrovski, Csortos: "TIMAP-protein phosphatase 1-complex controls endothelin-1 production via ECE-1 dephosphorylation." in: The international journal of biochemistry & cell biology, Vol. 73, pp. 11-18, (2016) (PubMed).

Target Details for PPP1R16B

Target: PPP1R16B (Protein Phosphatase 1, Regulatory Subunit 16B (PPP1R16B))

Alternative Name: PPP1R16B (PPP1R16B Products)

Background: The protein encoded by this gene is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and may act as a signaling molecule through interaction with protein phosphatase-1. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Molecular Weight: 63551

Gene ID: 26051

NCBI Accession: NP_001166206, NP_056383

UniProt: Q96T49