This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This UBASH3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-340 amino acids from the Central region of human UBASH3A.
UBASH3A antibody, CLIP4 antibody, STS-2 antibody, TULA antibody, TULA-1 antibody, 5830413C03Rik antibody, C330001M22 antibody, Sts-2 antibody, ubiquitin associated and SH3 domain containing A antibody, ubiquitin associated and SH3 domain containing, A antibody, UBASH3A antibody, Ubash3a antibody
Background
UBASH3A interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface.