This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ZKSCAN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 238-265 amino acids from the Central region of human ZKSCAN1.
The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links (summarized by Tommerup and Vissing, 1995 [PubMed 7557990]). Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. See ZNF91 (MIM 603971) for general information on zinc finger proteins.[supplied by OMIM].