This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PPP4R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-254 amino acids from the Central region of human PPP4R2.
PP4R2 antibody, BE691708 antibody, C230060M08Rik antibody, ppp4r2 antibody, fe11b04 antibody, wu:fe11b04 antibody, ppp4r2-B antibody, wu:fa17h08 antibody, wu:fc23g05 antibody, protein phosphatase 4 regulatory subunit 2 antibody, protein phosphatase 4, regulatory subunit 2 antibody, protein phosphatase 4, regulatory subunit 2a antibody, protein phosphatase 4 regulatory subunit 2 S homeolog antibody, protein phosphatase 4 regulatory subunit 2 L homeolog antibody, protein phosphatase 4, regulatory subunit 2b antibody, PPP4R2 antibody, Ppp4r2 antibody, ppp4r2a antibody, ppp4r2.S antibody, ppp4r2 antibody, ppp4r2.L antibody, ppp4r2b antibody
Background
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.