MRPS31 antibody (AA 219-247)

Catalog No. ABIN1538106

Product Details anti-MRPS31 Antibody

Target: MRPS31 (Mitochondrial Ribosomal Protein S31 (MRPS31))

Binding Specificity: AA 219-247

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS31 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MRPS31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-247 amino acids from the Central region of human MRPS31.

Clone: RB37345

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: MRPS31 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for MRPS31

Target: MRPS31 (Mitochondrial Ribosomal Protein S31 (MRPS31))

Alternative Name: MRPS31 (MRPS31 Products)

Synonyms: IMOGN38 antibody, MRP-S31 antibody, S31mt antibody, 1500002D03Rik antibody, AA960481 antibody, Imogen38 antibody, Imogen44 antibody, mitochondrial ribosomal protein S31 antibody, MRPS31 antibody, Mrps31 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes, however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13. [provided by RefSeq].

Molecular Weight: 45318

Gene ID: 10240

NCBI Accession: NP_005821

UniProt: Q92665