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APC antibody (AA 1148-1176)

APC Reactivity: Mouse WB Host: Rabbit Polyclonal RB37442 unconjugated
Catalog No. ABIN1537771
  • Target See all APC Antibodies
    APC (Adenomatous Polyposis Coli (APC))
    Binding Specificity
    • 21
    • 15
    • 10
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1148-1176
    Reactivity
    • 64
    • 41
    • 34
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 94
    • 8
    • 4
    • 2
    Rabbit
    Clonality
    • 86
    • 22
    Polyclonal
    Conjugate
    • 58
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This APC antibody is un-conjugated
    Application
    • 50
    • 31
    • 30
    • 27
    • 26
    • 18
    • 18
    • 11
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This APC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1148-1176 amino acids from the Central region of human APC.
    Clone
    RB37442
    Isotype
    Ig Fraction
    Top Product
    Discover our top product APC Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    APC Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Expiry Date
    6 months
  • Target
    APC (Adenomatous Polyposis Coli (APC))
    Alternative Name
    APC (APC Products)
    Synonyms
    dp2 antibody, dp3 antibody, fap antibody, fpc antibody, xapc antibody, dp2.5 antibody, AI047805 antibody, AU020952 antibody, AW124434 antibody, CC1 antibody, Min antibody, mAPC antibody, BTPS2 antibody, DP2 antibody, DP2.5 antibody, DP3 antibody, GS antibody, PPP1R46 antibody, RATAPC antibody, APC1 antibody, APC, WNT signaling pathway regulator antibody, adenomatous polyposis coli antibody, adenomatous polyposis coli protein, putative antibody, adenomatosis polyposis coli antibody, adenomatous polyposis coli L homeolog antibody, APC antibody, apc antibody, Smp_139190 antibody, Apc antibody, apc.L antibody
    Background
    This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
    Molecular Weight
    311646
    Gene ID
    324
    NCBI Accession
    NP_000029, NP_001120982
    UniProt
    P25054
    Pathways
    WNT Signaling, Stem Cell Maintenance, Cell-Cell Junction Organization
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