Fatty Acid Synthase antibody (AA 942-973)

Catalog No. ABIN1537694

Product Details anti-Fatty Acid Synthase Antibody

Target: Fatty Acid Synthase (FASN)

Binding Specificity: AA 942-973

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fatty Acid Synthase antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This FASN antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 942-973 amino acids from the Central region of human FASN.

Clone: 497CT15-2-5

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:500-1:2000. IF: 1:200. IF: 1:25. IF: 1:25. WB: 1:100. WB: 1:8000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: FASN Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Alternative Name: FASN (FASN Products)

Background: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Molecular Weight: 273427

Gene ID: 2194

NCBI Accession: NP_004095

UniProt: P49327

Pathways: AMPK Signaling