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TLE1 antibody (AA 199-228)
TLE1
Reactivity: Human
WB
Host: Mouse
Monoclonal
381CT18-5-1
unconjugated
Product Details anti-TLE1 Antibody
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Target
See all TLE1 Antibodies
TLE1
(Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
Binding Specificity
All epitopes for TLE1 antibodies
AA 199-228
Reactivity
All reactivities for TLE1 antibodies
Human
Host
All hosts for TLE1 antibodies
Mouse
Clonality
All clonalities for TLE1 antibodies
Monoclonal
Conjugate
All conjugates for TLE1 antibodies
This TLE1 antibody is un-conjugated
Application
All applications for TLE1 antibodies
Western Blotting (WB)
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Immunogen
This TLE1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 199-228 amino acids from the Central region of human TLE1.
Clone
381CT18-5-1
Isotype
IgG1
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Discover our top product TLE1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:100~250
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
TLE1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
Expiry Date
6 months
Target Details for TLE1
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Target
TLE1
(Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
Alternative Name
TLE1 (TLE1 Products )
Synonyms
ESG antibody, ESG1 antibody, GRG1 antibody, C230057C06Rik antibody, Estm14 antibody, Grg1 antibody, Tle4l antibody, TLE1 antibody, transducin like enhancer of split 1 antibody, transducin-like enhancer protein 1 antibody, transducin-like enhancer of split 1 antibody, transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) antibody, TLE1 antibody, Smp_150080 antibody, Tle1 antibody, LOC100354911 antibody, LOC100524475 antibody, LOC100061341 antibody
Background
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Molecular Weight
83201
Gene ID
7088
NCBI Accession
NP_005068
UniProt
Q04724
Pathways
WNT Signaling , SARS-CoV-2 Protein Interactome
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