This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PIGO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 955-983 amino acids from the C-terminal region of human PIGO.
HPMRS2 antibody, RP11-182N22.4 antibody, mFLJ00350 antibody, phosphatidylinositol glycan anchor biosynthesis class O antibody, phosphatidylinositol glycan anchor biosynthesis, class O antibody, PIGO antibody, Pigo antibody
Background
This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least two alternatively spliced transcripts encoding distinct isoforms have been found for this gene.