DMGDH antibody (C-Term)

Catalog No. ABIN1537626

Product Details anti-DMGDH Antibody

Target: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Binding Specificity: AA 836-864, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMGDH antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DMGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 836-864 amino acids from the C-terminal region of human DMGDH.

Clone: RB23867

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: DMGDH Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for DMGDH

Target: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Alternative Name: DMGDH (DMGDH Products)

Synonyms: MGC132281 antibody, DMGDHD antibody, ME2GLYDH antibody, Me2GlyDH antibody, 1200014D15Rik antibody, AI787269 antibody, dimethylglycine dehydrogenase antibody, dimethylglycine dehydrogenase L homeolog antibody, D-amino-acid oxidase antibody, Dimethylglycine dehydrogenase antibody, glycine cleavage system protein T antibody, dimethylglycine dehydrogenase precursor antibody, DMGDH antibody, dmgdh.L antibody, dmgdh antibody, SAR11_1253 antibody, EAMY_RS27375 antibody, EAMY_RS33570 antibody, VDBG_06516 antibody, Sinme_2570 antibody, HALXA_RS03495 antibody, Dmgdh antibody

Background: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum.

Molecular Weight: 96811

Gene ID: 29958

NCBI Accession: NP_037523

UniProt: Q9UI17