PRICKLE1 antibody (C-Term)

Catalog No. ABIN1537540

Product Details anti-PRICKLE1 Antibody

Target: PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))

Binding Specificity: AA 678-704, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRICKLE1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PRICKLE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 678-704 amino acids from the C-terminal region of human PRICKLE1.

Clone: RB39636

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PRICKLE1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for PRICKLE1

Target: PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))

Alternative Name: PRICKLE1 (PRICKLE1 Products)

Synonyms: EPM1B antibody, RILP antibody, Rilp antibody, 1110058P22Rik antibody, AW215793 antibody, Prickle antibody, mpk1 antibody, XPk antibody, pk-B antibody, prickle antibody, prickle-B antibody, Prickle-b antibody, prickle planar cell polarity protein 1 antibody, prickle planar cell polarity protein 1 L homeolog antibody, prickle planar cell polarity protein 1 S homeolog antibody, PRICKLE1 antibody, Prickle1 antibody, prickle1.L antibody, prickle1.S antibody

Background: This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3.

Molecular Weight: 94300

Gene ID: 144165

NCBI Accession: NP_001138353, NP_001138354, NP_001138355, NP_694571

UniProt: Q96MT3

Pathways: WNT Signaling, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus