TRAF3IP2 antibody (C-Term)

Catalog No. ABIN1537357

Product Details anti-TRAF3IP2 Antibody

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Binding Specificity: AA 463-492, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAF3IP2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TRAF3IP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 463-492 amino acids from the C-terminal region of human TRAF3IP2.

Clone: RB39771

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: TRAF3IP2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for TRAF3IP2

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Alternative Name: TRAF3IP2 (TRAF3IP2 Products)

Synonyms: ACT1 antibody, C6orf2 antibody, C6orf4 antibody, C6orf5 antibody, C6orf6 antibody, CIKS antibody, PSORS13 antibody, AI429613 antibody, Act1 antibody, RGD1304768 antibody, C6ORF4 antibody, t3jam antibody, traf3ip2 antibody, TRAF3IP2 antibody, MGC134034 antibody, TRAF3 interacting protein 2 antibody, Traf3 interacting protein 2 antibody, adapter protein CIKS antibody, TRAF3 interacting protein 2 L homeolog antibody, TRAF3IP2 antibody, Traf3ip2 antibody, LOC100473939 antibody, traf3ip3.L antibody, traf3ip3 antibody

Background: This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.

Molecular Weight: 64666

Gene ID: 10758

NCBI Accession: NP_001157753, NP_001157755, NP_679211

UniProt: O43734

Pathways: Production of Molecular Mediator of Immune Response