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LKB1 antibody (C-Term)
STK11
Reactivity: Human
IHC (p)
Host: Rabbit
Polyclonal
RB3549-3550
unconjugated
Product Details anti-LKB1 Antibody
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Target
See all LKB1 (STK11) Antibodies
LKB1 (STK11)
(serine/threonine Kinase 11 (STK11))
Binding Specificity
All epitopes for LKB1 antibodies
AA 387-417, C-Term
Reactivity
All reactivities for LKB1 antibodies
Human
Host
All hosts for LKB1 antibodies
Rabbit
Clonality
All clonalities for LKB1 antibodies
Polyclonal
Conjugate
All conjugates for LKB1 antibodies
This LKB1 antibody is un-conjugated
Application
All applications for LKB1 antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This STK11 (LKB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-417 amino acids from the C-terminal region of human STK11 (LKB1).
Clone
RB3549-3550
Isotype
Ig Fraction
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Discover our top product STK11 Primary Antibody
Alternatives
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Application Details
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Application Notes
IHC-P: 1:50~100
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
References for anti-LKB1 antibody (ABIN1537274)
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Dahmani, Just, Delay, Canal, Finzi, Prip-Buus, Lambert, Sujobert, Buchet-Poyau, Miller, Cavard, Marmier, Terris, Billaud, Perret : "A novel LKB1 isoform enhances AMPK metabolic activity and displays oncogenic properties. " in: Oncogene , Vol. 34 , Issue 18 , pp. 2337-46 , (2015 ) (PubMed ).
Target Details for LKB1
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Target
LKB1 (STK11)
(serine/threonine Kinase 11 (STK11))
Alternative Name
STK11 (LKB1) (STK11 Products )
Background
STK11, is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.
Molecular Weight
48636
Gene ID
6794
NCBI Accession
NP_000446
UniProt
Q15831
Pathways
AMPK Signaling , Carbohydrate Homeostasis , Regulation of Carbohydrate Metabolic Process , Warburg Effect
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