This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PNMA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-412 amino acids from the C-terminal region of human PNMA3.
MA3 antibody, MA5 antibody, RGD1563752 antibody, PNMA family member 3 antibody, paraneoplastic antigen MA3 antibody, paraneoplastic Ma antigen 3 antibody, PNMA3 antibody, Pnma3 antibody
Background
This gene is a member of the paraneoplastic antigen MA (PNMA) gene family, whose protein products share homology with retroviral Gag proteins. They are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. [provided by RefSeq].