TRIM68 antibody (C-Term)

Catalog No. ABIN1537236

Product Details anti-TRIM68 Antibody

Target: TRIM68 (Tripartite Motif Containing 68 (TRIM68))

Binding Specificity: AA 382-411, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM68 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TRIM68 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 382-411 amino acids from the C-terminal region of human TRIM68.

Clone: RB36638

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: TRIM68 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

References for anti-TRIM68 antibody (ABIN1537236)

Tan, Liu, Yu, Wang, Tang, Wang, Fu: "Lentivirus-mediated RNA interference of tripartite motif 68 inhibits the proliferation of colorectal cancer cell lines SW1116 and HCT116 in vitro." in: Oncology letters, Vol. 13, Issue 4, pp. 2649-2655, (2017) (PubMed).

Target Details for TRIM68

Target: TRIM68 (Tripartite Motif Containing 68 (TRIM68))

Alternative Name: TRIM68 (TRIM68 Products)

Synonyms: GC109 antibody, RNF137 antibody, SS-56 antibody, SS56 antibody, AI894158 antibody, F730114J12Rik antibody, Rnf137 antibody, TRIM68 antibody, tripartite motif containing 68 antibody, tripartite motif-containing 68 antibody, E3 ubiquitin-protein ligase TRIM68 antibody, TRIM68 antibody, Trim68 antibody, LOC100053519 antibody

Background: The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is expressed in many cancer cell lines. Its expression in normal tissues, however, was found to be restricted to prostate. This gene was also found to be differentially expressed in androgen-dependent versus androgen-independent prostate cancer cells.

Molecular Weight: 56259

Gene ID: 55128

NCBI Accession: NP_060543

UniProt: Q6AZZ1

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling