This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This RPA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-261 amino acids from the C-terminal region of human RPA4.
HSU24186 antibody, replication protein A4 antibody, RPA4 antibody
Background
This gene encodes a single-stranded DNA-binding protein that is the 30- kDa subunit of the replication protein A complex. Replication protein A is an essential factor for DNA double-strand break repair and cell cycle checkpoint activation. The encoded protein localizes to DNA repair foci and may be involved in the cellular DNA damage response. This protein may also play a role in inhibiting viral replication.