TEF antibody (C-Term)

Catalog No. ABIN1536856

Product Details anti-TEF Antibody

Target: TEF (Thyrotrophic Embryonic Factor (TEF))

Binding Specificity: AA 213-240, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TEF antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: C, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-240 amino acids from the C-terminal region of human TEF.

Clone: RB39904

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: TEF Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for TEF

Target: TEF (Thyrotrophic Embryonic Factor (TEF))

Alternative Name: TEF (TEF Products)

Background: Thyrotroph embryonic factor (TEF), a transcription factor, is a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP), VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Molecular Weight: 33248

Gene ID: 7008

NCBI Accession: NP_001138870, NP_003207

UniProt: Q10587