OSCAR antibody (C-Term)

Catalog No. ABIN1536842

Product Details anti-OSCAR Antibody

Target: OSCAR (Osteoclast Associated Receptor (OSCAR))

Binding Specificity: AA 205-231, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OSCAR antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This OSCAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-231 amino acids from the C-terminal region of human OSCAR.

Clone: RB39599

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: OSCAR Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for OSCAR

Target: OSCAR (Osteoclast Associated Receptor (OSCAR))

Alternative Name: OSCAR (OSCAR Products)

Synonyms: OSCAR antibody, mOSCAR-M3 antibody, mOSCAR antibody, mOSCAR-M1 antibody, mOSCAR-M2 antibody, PIGR3 antibody, PIgR-3 antibody, RGD1559897 antibody, osteoclast associated, immunoglobulin-like receptor antibody, osteoclast-associated immunoglobulin-like receptor antibody, osteoclast associated receptor antibody, OSCAR antibody, LOC748876 antibody, Oscar antibody

Background: Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 30481

Gene ID: 126014

NCBI Accession: NP_001269278, NP_001269279, NP_570127, NP_573398, NP_573399, NP_996554

UniProt: Q8IYS5