Der1-Like Domain Family, Member 2 (DERL2) (AA 191-219), (C-Term) antibody
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- Target See all Der1-Like Domain Family, Member 2 (DERL2) Antibodies
- Der1-Like Domain Family, Member 2 (DERL2)
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Binding Specificity
- AA 191-219, C-Term
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This Mouse Derl2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the C-terminal region of mouse Derl2.
- Clone
- RB40190
- Isotype
- Ig Fraction
- Top Product
- Discover our top product DERL2 Primary Antibody
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- Application Notes
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Mouse Derl2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- Expiry Date
- 6 months
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- Target
- Der1-Like Domain Family, Member 2 (DERL2)
- Alternative Name
- Derl2 (DERL2 Products)
- Background
- Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate (By similarity).
- Molecular Weight
- 27640
- Gene ID
- 116891
- NCBI Accession
- NP_291040
- UniProt
- Q8BNI4
- Pathways
- ER-Nucleus Signaling, Feeding Behaviour
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