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Der1-Like Domain Family, Member 2 (DERL2) (AA 191-219), (C-Term) antibody

DERL2 Reactivity: Mouse WB Host: Rabbit Polyclonal RB40190 unconjugated
Catalog No. ABIN1536818
  • Target See all Der1-Like Domain Family, Member 2 (DERL2) Antibodies
    Der1-Like Domain Family, Member 2 (DERL2)
    Binding Specificity
    • 8
    • 7
    • 5
    • 2
    AA 191-219, C-Term
    Reactivity
    • 15
    • 13
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 22
    Rabbit
    Clonality
    • 22
    Polyclonal
    Conjugate
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    Un-conjugated
    Application
    • 21
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Derl2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the C-terminal region of mouse Derl2.
    Clone
    RB40190
    Isotype
    Ig Fraction
    Top Product
    Discover our top product DERL2 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Mouse Derl2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Expiry Date
    6 months
  • Target
    Der1-Like Domain Family, Member 2 (DERL2)
    Alternative Name
    Derl2 (DERL2 Products)
    Background
    Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate (By similarity).
    Molecular Weight
    27640
    Gene ID
    116891
    NCBI Accession
    NP_291040
    UniProt
    Q8BNI4
    Pathways
    ER-Nucleus Signaling, Feeding Behaviour
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