CRYBB3 antibody (C-Term)

Catalog No. ABIN1536797

Product Details anti-CRYBB3 Antibody

Target: CRYBB3 (CRYbB3) (Crystallin, beta B3 (CRYbB3))

Binding Specificity: AA 179-207, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRYBB3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CRYBB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-207 amino acids from the C-terminal region of human CRYBB3.

Clone: RB30428

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CRYBB3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for CRYBB3

Target: CRYBB3 (CRYbB3) (Crystallin, beta B3 (CRYbB3))

Alternative Name: CRYBB3 (CRYbB3 Products)

Synonyms: MGC84109 antibody, CATCN2 antibody, CRYB3 antibody, CTRCT22 antibody, AI852419 antibody, crystallin beta B3 L homeolog antibody, crystallin beta B3 antibody, crystallin, beta B3 antibody, crybb3.L antibody, CRYBB3 antibody, crybb3 antibody, Crybb3 antibody

Background: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B2. [provided by RefSeq].

Molecular Weight: 24252

Gene ID: 1417

NCBI Accession: NP_004067

UniProt: P26998