CHMP5 antibody (C-Term)

Catalog No. ABIN1536793

Product Details anti-CHMP5 Antibody

Target: CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))

Binding Specificity: AA 178-204, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP5 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CHMP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-204 amino acids from the C-terminal region of human CHMP5.

Clone: RB38584

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CHMP5 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for CHMP5

Target: CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))

Alternative Name: CHMP5 (CHMP5 Products)

Synonyms: SNF7DC2 antibody, cgi-34 antibody, hspc177 antibody, pnas-2 antibody, vps60 antibody, chmp5 antibody, zgc:64125 antibody, C9orf83 antibody, HSPC177 antibody, PNAS-2 antibody, Vps60 antibody, 2210412K09Rik antibody, AW545668 antibody, RGD1305968 antibody, charged multivesicular body protein 5 S homeolog antibody, charged multivesicular body protein 5b antibody, charged multivesicular body protein 5 antibody, charged multivesicular body protein 5 L homeolog antibody, chromatin modifying protein 5 antibody, chmp5.S antibody, chmp5b antibody, CHMP5 antibody, chmp5.L antibody, chmp5 antibody, Chmp5 antibody

Background: CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).

Molecular Weight: 24571

Gene ID: 51510

NCBI Accession: NP_001182465, NP_057494

UniProt: Q9NZZ3