This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This RREB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1398-1424 amino acids from the C-terminal region of human RREB1.
The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene.