This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This RRBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1327-1355 amino acids from the C-terminal region of human RRBP1.
Analysis of cDNA clones indicates that ribosome binding protein 1 may exist in different forms due to removal of tandem repeats, or partial intraexonic splicing of RRBP1. The form presented here is lacking the canine p180 ribosome-binding domain, NQGKKAEGAQ, which is tandemly repeated close to the N-terminus in other forms that haven't been fully characterized. RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome. Alternate splicing results in multiple transcript variants.