This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
Immunogen
This KCNJ3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 390-418 amino acids from the C-terminal region of human KCNJ3.
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.