NCOA2 antibody (pSer736)

Catalog No. ABIN1532157

Product Details anti-NCOA2 Antibody

Target: NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))

Binding Specificity: AA 702-751, pSer736

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity:

NCoA2 (Phospho-Ser736) Antibody detects endogenous levels of NCoA2 only when phosphorylated at Ser736.

PhosphorylationH:S736

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human NCoA2 around the phosphorylation site of Ser736.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.446678 (NCBI Gene Symbol: NCOA2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for NCOA2

Target: NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))

Alternative Name: NCoA2 (NCOA2 Products)

Background:

Synonyms: glucocorticoid receptor-interacting protein-1, GRIP1, NCoA-2, nuclear receptor coactivator 2, TIF2, transcriptional intermediary factor 2

NCBI Gene Symbol: NCOA2

Molecular Weight: 159 kDa

Gene ID: 10499

OMIM: 601993

UniProt: Q15596

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling