ITCH antibody (pTyr420)
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- Target See all ITCH Antibodies
- ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
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Binding Specificity
- AA 386-435, pTyr420
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ITCH antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Specificity
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ITCH (Phospho-Tyr420) Antibody detects endogenous levels of ITCH only when phosphorylated at Tyr420.
PhosphorylationH:Y420 M:Y381
- Purification
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
- Purity
- > 95 %
- Immunogen
- The antiserum was produced against synthesized peptide derived from human ITCH around the phosphorylation site of Tyr420.
- Isotype
- IgG
- Top Product
- Discover our top product ITCH Primary Antibody
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- Application Notes
- IHC: 1:50~1:100 ELISA: 1:20000
- Comment
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Unigene-Number: Hs.632272 (NCBI Gene Symbol: ITCH)
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Stable at -20°C for at least 1 year.
- Expiry Date
- 12 months
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- Target
- ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
- Alternative Name
- ITCH (ITCH Products)
- Synonyms
- AIF4 antibody, AIP4 antibody, NAPP1 antibody, dJ468O1.1 antibody, 6720481N21Rik antibody, 8030492O04Rik antibody, A130065M08 antibody, C230047C07Rik antibody, itchy E3 ubiquitin protein ligase antibody, itchy, E3 ubiquitin protein ligase antibody, ITCH antibody, Itch antibody
- Background
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Synonyms: AIF4, AIP4, atrophin-1-interacting protein 4, Itchy homolog E3 ubiquitin protein ligase, NAPP1, NFE2-associated polypeptide 1, ubiquitin protein ligase ITCH
NCBI Gene Symbol: ITCH
- Molecular Weight
- 102 kDa
- Gene ID
- 83737
- OMIM
- 606409
- UniProt
- Q96J02
- Pathways
- Activation of Innate immune Response, CXCR4-mediated Signaling Events
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