MAP3K8 antibody (pSer400)
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- Target See all MAP3K8 Antibodies
- MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))
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Binding Specificity
- AA 366-415, pSer400
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAP3K8 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Specificity
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MAP3K8 (Phospho-Ser400) Antibody detects endogenous levels of MAP3K8 only when phosphorylated at Ser400.
PhosphorylationH:S400 M:S400 R:S400
- Purification
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
- Purity
- > 95 %
- Immunogen
- The antiserum was produced against synthesized peptide derived from human MAP3K8 around the phosphorylation site of Ser400.
- Isotype
- IgG
- Top Product
- Discover our top product MAP3K8 Primary Antibody
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- Application Notes
- IHC: 1:50~1:100 ELISA: 1:1000
- Comment
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Unigene-Number: Hs.432453 (NCBI Gene Symbol: MAP3K8)
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Stable at -20°C for at least 1 year.
- Expiry Date
- 12 months
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- Target
- MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))
- Alternative Name
- MAP3K8 (MAP3K8 Products)
- Synonyms
- MAP3K8 antibody, COT antibody, EST antibody, ESTF antibody, MEKK8 antibody, TPL2 antibody, Tpl-2 antibody, c-COT antibody, Cot antibody, Cot/Tpl2 antibody, Est antibody, Estf antibody, Tpl2 antibody, D17TPL2 antibody, mitogen-activated protein kinase kinase kinase 8 antibody, MAP3K8 antibody, map3k8 antibody, Map3k8 antibody
- Background
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Synonyms: COT proto-oncogene serine/threonine-protein kinase, C-COT, Cancer Osaka thyroid oncogene, Tumor progression locus 2, TPL-2
NCBI Gene Symbol: MAP3K8
- Molecular Weight
- 52 kDa
- Gene ID
- 1326
- OMIM
- 191195
- UniProt
- P41279
- Pathways
- PI3K-Akt Signaling, TCR Signaling
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