PIKFYVE antibody (pSer307)

Catalog No. ABIN1531726

Product Details anti-PIKFYVE Antibody

Target: PIKFYVE (phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE))

Binding Specificity: AA 273-322, pSer307

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIKFYVE antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Specificity:

PIP5K (Phospho-Ser307) Antibody detects endogenous levels of PIP5K only when phosphorylated at Ser307.

PhosphorylationH:S307 M:S318 R:S357

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PIP5K around the phosphorylation site of Ser307.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:10000

Comment:

Unigene-Number: Hs.173939 (NCBI Gene Symbol: PIKFYVE)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for PIKFYVE

Target: PIKFYVE (phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE))

Alternative Name: PIP5K (PIKFYVE Products)

Background:

Synonyms: 1- phosphatidylinositol-4-phosphate 5-kinase, FYV1, FYVE finger-containing phosphoinositide kinase, KIAA0981, PIKfyve, PIP5K3, PtdIns(4)P-5- kinase, p235

NCBI Gene Symbol: PIKFYVE

Molecular Weight: 237 kDa

Gene ID: 200576

OMIM: 121850

UniProt: Q9Y2I7

Pathways: Inositol Metabolic Process