CXCR2 antibody (pSer347)

Catalog No. ABIN1531669

Product Details anti-CXCR2 Antibody

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Binding Specificity: AA 311-360, pSer347

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Specificity:

IL-8R beta/CDw128 beta (Phospho-Ser347) Antibody detects endogenous levels of IL-8R beta/CDw128 beta only when phosphorylated at Ser347.

PhosphorylationH:S347 M:S346

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human IL-8R beta/CDw128 beta around the phosphorylation site of Ser347.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000

Comment:

Unigene-Number: Hs.846 (NCBI Gene Symbol: CXCR2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for CXCR2

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Alternative Name: IL-8R beta/cdw128 beta (CXCR2 Products)

Synonyms: CD182 antibody, CDw128b antibody, CMKAR2 antibody, IL8R2 antibody, IL8RA antibody, IL8RB antibody, CXC-R2 antibody, CXCR-2 antibody, CD128 antibody, CDw128 antibody, Cmkar2 antibody, Gpcr16 antibody, IL-8Rh antibody, IL-8rb antibody, Il8rb antibody, mIL-8RH antibody, C-X-C motif chemokine receptor 2 antibody, chemokine (C-X-C motif) receptor 2 antibody, Cxcr2 antibody, CXCR2 antibody

Background:

Synonyms: High affinity interleukin-8 receptor B, IL-8R B, CXCR-2, GRO/MGSA receptor, IL-8 receptor type 2, CD182 antigen, CDw128b, IL8RB, CXCR2

NCBI Gene Symbol: CXCR2

Molecular Weight: 40 kDa

Gene ID: 3579

OMIM: 146928

UniProt: P25025

Pathways: cAMP Metabolic Process