RYR2 antibody (pSer2808)

Catalog No. ABIN1531389

Product Details anti-RYR2 Antibody

Target: RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

Binding Specificity: AA 2774-2823, pSer2808

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RYR2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Specificity:

RyR2 (Phospho-Ser2808) Antibody detects endogenous levels of RyR2 only when phosphorylated at Ser2808.

PhosphorylationH:S2808 M:S2808 R:S2798

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human RyR2 around the phosphorylation site of Ser2808.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.109514 (NCBI Gene Symbol: RYR2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for RYR2

Target: RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

Alternative Name: RyR2 (RYR2 Products)

Background:

Synonyms: cardiac muscle ryanodine receptor-calcium release channel, cardiac muscle-type ryanodine receptor, ryanodine receptor 2, RYR-2

NCBI Gene Symbol: RYR2

Molecular Weight: 564 kDa

Gene ID: 6262

OMIM: 180902

UniProt: Q92736

Pathways: Myometrial Relaxation and Contraction