CHEK2 antibody (pThr387)
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- Target See all CHEK2 Antibodies
- CHEK2 (Checkpoint Kinase 2 (CHEK2))
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Binding Specificity
- AA 361-410, pThr387
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CHEK2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
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Chk2 (Phospho-Thr387) Antibody detects endogenous levels of Chk2 only when phosphorylated at Thr387.
PhosphorylationH:T387 M:T391 R:T390
- Purification
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
- Purity
- > 95 %
- Immunogen
- The antiserum was produced against synthesized peptide derived from human Chk2 around the phosphorylation site of Thr387.
- Isotype
- IgG
- Top Product
- Discover our top product CHEK2 Primary Antibody
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- Application Notes
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000
- Comment
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Unigene-Number: Hs.291363, Hs.505297 (NCBI Gene Symbol: CHEK2)
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Stable at -20°C for at least 1 year.
- Expiry Date
- 12 months
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- Target
- CHEK2 (Checkpoint Kinase 2 (CHEK2))
- Alternative Name
- Chk2 (CHEK2 Products)
- Synonyms
- CDS1 antibody, CHK2 antibody, HuCds1 antibody, LFS2 antibody, PP1425 antibody, RAD53 antibody, hCds1 antibody, fa66f08 antibody, wu:fa66f08 antibody, zgc:55865 antibody, Cds1 antibody, HUCDS1 antibody, Rad53 antibody, Chk2 antibody, cds1 antibody, chek2 antibody, chk2 antibody, hucds1 antibody, lfs2 antibody, pp1425 antibody, rad53 antibody, checkpoint kinase 2 antibody, serine/threonine-protein kinase chk2 antibody, checkpoint kinase 2 L homeolog antibody, CHEK2 antibody, chek2 antibody, Chek2 antibody, MCYG_07308 antibody, chek2.L antibody
- Background
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Synonyms: Cds1, CHEK2, CHK2, Chk2, CHK2 checkpoint homolog (S. pombe), kinase Chk2, RAD53
NCBI Gene Symbol: CHEK2
- Molecular Weight
- 60 kDa
- Gene ID
- 11200
- OMIM
- 176807
- UniProt
- O96017
- Pathways
- p53 Signaling, Apoptosis, Cell Division Cycle
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