Caspase 8 antibody (pSer347)
-
- Target See all Caspase 8 (CASP8) Antibodies
- Caspase 8 (CASP8)
-
Binding Specificity
- AA 313-362, pSer347
-
Reactivity
- Human, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This Caspase 8 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificity
-
Caspase 8 (Phospho-Ser347) Antibody detects endogenous levels of Caspase 8 only when phosphorylated at Ser347.
PhosphorylationH:S347 R:S349
- Purification
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
- Purity
- > 95 %
- Immunogen
- The antiserum was produced against synthesized peptide derived from human Caspase 8 around the phosphorylation site of Ser347.
- Isotype
- IgG
- Top Product
- Discover our top product CASP8 Primary Antibody
-
-
- Application Notes
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000
- Comment
-
Unigene-Number: Hs.599762 (NCBI Gene Symbol: CASP8)
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Stable at -20°C for at least 1 year.
- Expiry Date
- 12 months
-
- Target
- Caspase 8 (CASP8)
- Alternative Name
- Caspase 8 (CASP8 Products)
- Synonyms
- casp8-A antibody, xCaspase-8 antibody, casp8 antibody, CASP8 antibody, CASP-8 antibody, FLICE antibody, MACH antibody, Mch5 antibody, ALPS2B antibody, CAP4 antibody, Casp-8 antibody, MCH5 antibody, caspase-8 antibody, zgc:92075 antibody, caspase 8 L homeolog antibody, death related ced-3/Nedd2-like protein antibody, caspase 8 antibody, caspase-8 antibody, caspase-8-like antibody, caspase 8, apoptosis-related cysteine peptidase antibody, casp8.L antibody, LOC661095 antibody, CASP8 antibody, LOC5563818 antibody, casp8 antibody, LOC100222284 antibody, Casp8 antibody
- Background
-
Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8 precursor, FADD-homologous ICE/CED-3- like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, ICE8, MACH, MCH5, MORT1-associated CED-3 homolog
NCBI Gene Symbol: CASP8
- Molecular Weight
- 55 kDa
- Gene ID
- 841
- OMIM
- 211980
- UniProt
- Q14790
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
-