MTHFR antibody (AA 1-230)

Catalog No. ABIN1513224

Product Details anti-MTHFR Antibody

Target: MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))

Binding Specificity: AA 1-230

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTHFR antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MVNEARGNSS LNPCLEGSAS SGSESSKDSS RCSTPGLDPE RHERLREKMR RRLESGDKWF SLEFFPPRTA EGAVNLISRF DRMAAGGPLY IDVTWHPAGD PGSDKETSSM MIASTAVNYC GLETILHMTC CRQRLEEITG HLHKAKQLGL KNIMALRGDP IGDQWEEEEG GFNYAVDLVK HIRSEFGDYF DICVAGYPKG HPEAGSFEAD LKHLKEKVSA GADFIITQLF

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human MTHFR (NP_005948.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MTHFR

Target: MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))

Alternative Name: MTHFR (MTHFR Products)

Synonyms: DDBDRAFT_0204686 antibody, DDBDRAFT_0230137 antibody, DDB_0204686 antibody, DDB_0230137 antibody, AI323986 antibody, methylenetetrahydrofolate reductase (NAD(P)H) L homeolog antibody, methylenetetrahydrofolate reductase antibody, methylenetetrahydrofolate reductase (NAD(P)H) antibody, 5,10-methylenetetrahydrofolate reductase antibody, mthfr.L antibody, MTHFR antibody, mthfr antibody, metF antibody, DDB_G0279137 antibody, Mthfr antibody

Background: The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.,MTHFR,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,MTHFR

Molecular Weight: 75 kDa

Gene ID: 4524

UniProt: P42898

Pathways: Methionine Biosynthetic Process