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CD8 alpha antibody

CD8A Reactivity: Human IHC, WB Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN7101333
  • Target See all CD8 alpha (CD8A) Antibodies
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Reactivity
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    Human
    Host
    • 122
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    • 85
    Rabbit
    Clonality
    • 227
    • 98
    • 1
    Monoclonal
    Conjugate
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    This CD8 alpha antibody is un-conjugated
    Application
    • 255
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    Immunohistochemistry (IHC), Western Blotting (WB)
    Cross-Reactivity
    Human
    Characteristics
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthesized peptide derived from human CD8A
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Alternative Name
    CD8A (CD8A Products)
    Synonyms
    cd8 antibody, LOC100136450 antibody, BB154331 antibody, Ly-2 antibody, Ly-35 antibody, Ly-B antibody, Lyt-2 antibody, zgc:136643 antibody, CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody, RHACD8-4 antibody, CD8a molecule antibody, uncharacterized LOC100125537 antibody, CD8 alpha antibody, CD8 antigen, alpha chain antibody, T-cell surface glycoprotein CD8 alpha chain antibody, Cd8a antibody, LOC100125537 antibody, LOC100136450 antibody, CD8A antibody, cd8a antibody, LOC100126556 antibody
    Background
    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],CD8, Leu2, MAL, p32,CDs,Immunology & Inflammation,Stem Cells,CD8A
    Molecular Weight
    32 kDa
    Gene ID
    925
    UniProt
    P01732
    Pathways
    TCR Signaling
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