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CXCR4 antibody (AA 1-100)

CXCR4 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1512796
  • Target See all CXCR4 Antibodies
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    Binding Specificity
    • 18
    • 15
    • 15
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivity
    • 131
    • 84
    • 66
    • 21
    • 11
    • 11
    • 10
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 112
    • 22
    • 10
    • 5
    • 1
    Rabbit
    Clonality
    • 120
    • 30
    Polyclonal
    Conjugate
    • 96
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CXCR4 antibody is un-conjugated
    Application
    • 110
    • 51
    • 46
    • 36
    • 27
    • 27
    • 25
    • 25
    • 18
    • 11
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Sequence
    MEGISIYTSD NYTEEMGSGD YDSMKEPCFR EENANFNKIF LPTIYSIIFL TGIVGNGLVI LVMGYQKKLR SMTDKYRLHL SVADLLFVIT LPFWAVDAVA
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CXCR4 (NP_003458.1).
    Isotype
    IgG
    Top Product
    Discover our top product CXCR4 Primary Antibody
  • Application Notes
    WB,1:500 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    Alternative Name
    CXCR4 (CXCR4 Products)
    Background
    This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.,CD184,D2S201E,FB22,HM89,HSY3RR,LAP-3,LAP3,LCR1,LESTR,NPY3R,NPYR,NPYRL,NPYY3R,WHIM,WHIMS,CXCR4,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,Chemokines,Chemokine,Neuroscience,Stem Cells,Endothelial Progenitors,Hematopoietic Progenitors,Neural Stem Cells,Cardiovascular,Angiogenesis,CXCR4
    Molecular Weight
    39 kDa/40 kDa
    Gene ID
    7852
    UniProt
    P61073
    Pathways
    Regulation of Cell Size, CXCR4-mediated Signaling Events
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