ALPL antibody (AA 20-270)

Catalog No. ABIN1512569

Product Details anti-ALPL Antibody

Target: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Binding Specificity: AA 20-270

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALPL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: PEKEKDPKYW RDQAQETLKY ALELQKLNTN VAKNVIMFLG DGMGVSTVTA ARILKGQLHH NPGEETRLEM DKFPFVALSK TYNTNAQVPD SAGTATAYLC GVKANEGTVG VSAATERSRC NTTQGNEVTS ILRWAKDAGK SVGIVTTTRV NHATPSAAYA HSADRDWYSD NEMPPEALSQ GCKDIAYQLM HNIRDIDVIM GGGRKYMYPK NKTDVEYESD EKARGTRLDG LDLVDTWKSF KPRYKHSHFI W

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-270 of human Alkaline Phosphatase (Alkaline Phosphatase (ALPL)) (NP_000469.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ALPL

Target: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Alternative Name: ALPL (ALPL Products)

Synonyms: ALP antibody, iap antibody, alpl antibody, AP-TNAP antibody, APTNAP antibody, HOPS antibody, TNAP antibody, TNSALP antibody, Akp-2 antibody, Akp2 antibody, PHOA antibody, TNS-AP antibody, alkaline phosphatase, liver/bone/kidney L homeolog antibody, alkaline phosphatase, liver/bone/kidney antibody, alkaline phosphatase, intestinal, gene 2 antibody, alkaline phosphatase, liver/bone/kidney pseudogene antibody, alpl.L antibody, ALPL antibody, alpi.2 antibody, LOC100031702 antibody, Alpl antibody

Background: This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects.,ALPL,AP-TNAP,APTNAP,HOPS,TNAP,Kinase,Cell Biology & Developmental Biology,Cell Cycle,Stem Cells,ALPL

Molecular Weight: 48 kDa/51 kDa/57 kDa

Gene ID: 249

UniProt: P05186